Thiamin (vitamin B1) is a water soluble vitamin that supports glucose metabolism and normal growth and development.* Natural Factors BioCoenzymated formula contains a specialized combination of benfotiamine and sulbutiamine which are coenzyme forms of vitamin B1. Taking benfotiamine and sulbutiamine allows for greater absorption and bioavailability than non-coenzyme forms. Benfotiamine is fat soluble which allows it to cross cell membranes. Furthermore, it stimulates transketolase, the enzyme essential for maintaining normal glucose metabolic pathways.* It also supports healthy nervous system function and helps protect the body’s tissues against advanced glycation end products (AGEs).* Natural Factors BioCoenzymated Benfotiamine with sulbutiamine is truly the next generation B1!